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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG3
All Species:
14.24
Human Site:
S242
Identified Species:
26.11
UniProt:
P49916
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49916
NP_002302.2
1009
112907
S242
N
S
G
E
A
P
S
S
P
T
P
K
R
S
L
Chimpanzee
Pan troglodytes
XP_511409
922
102716
L223
V
Y
L
T
V
K
L
L
L
P
G
V
I
K
T
Rhesus Macaque
Macaca mulatta
XP_001113780
1009
112805
S242
N
S
G
E
A
P
S
S
P
T
P
K
R
S
L
Dog
Lupus familis
XP_548265
991
110592
S243
N
S
G
E
A
R
S
S
P
T
P
K
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P97386
1015
113000
S243
N
N
S
E
Q
A
P
S
S
P
A
P
G
T
S
Rat
Rattus norvegicus
NP_001012011
943
105425
S243
N
N
S
E
Q
D
P
S
S
P
A
P
K
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006215
902
101303
K203
I
I
Q
D
F
L
K
K
G
S
G
G
D
G
F
Frog
Xenopus laevis
NP_001082183
988
110688
H223
T
A
K
C
D
P
K
H
K
D
C
L
L
R
E
Zebra Danio
Brachydanio rerio
NP_001025345
752
84159
V53
E
M
K
E
W
Y
H
V
K
C
I
F
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650187
806
90830
D107
F
S
R
I
F
N
A
D
Q
Q
Q
M
H
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27474
773
86292
E74
N
Q
L
G
P
S
Y
E
G
L
E
L
G
V
A
Sea Urchin
Strong. purpuratus
XP_786357
875
97201
P176
D
G
S
D
P
K
H
P
D
N
S
F
R
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
T56
K
N
K
P
T
E
G
T
P
S
P
K
K
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
97.7
89.4
N.A.
87.3
82.4
N.A.
N.A.
71.3
68.2
55.7
N.A.
34.9
N.A.
23.3
48.4
Protein Similarity:
100
91.1
98.8
92.2
N.A.
91.3
86.4
N.A.
N.A.
78.9
79.6
64.9
N.A.
48.1
N.A.
39.3
62.9
P-Site Identity:
100
0
100
86.6
N.A.
20
20
N.A.
N.A.
0
6.6
13.3
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
0
100
86.6
N.A.
33.3
40
N.A.
N.A.
13.3
13.3
13.3
N.A.
13.3
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
24
8
8
0
0
0
16
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
8
0
0
16
8
8
0
8
8
8
0
0
8
0
8
% D
% Glu:
8
0
0
47
0
8
0
8
0
0
8
0
8
8
8
% E
% Phe:
8
0
0
0
16
0
0
0
0
0
0
16
0
0
8
% F
% Gly:
0
8
24
8
0
0
8
0
16
0
16
8
16
8
0
% G
% His:
0
0
0
0
0
0
16
8
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
8
0
8
0
0
% I
% Lys:
8
0
24
0
0
16
16
8
16
0
0
31
16
16
0
% K
% Leu:
0
0
16
0
0
8
8
8
8
8
0
16
8
8
31
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
47
24
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
16
24
16
8
31
24
31
16
0
0
0
% P
% Gln:
0
8
8
0
16
0
0
0
8
8
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
24
8
0
% R
% Ser:
0
31
24
0
0
8
24
39
16
16
8
0
0
31
24
% S
% Thr:
8
0
0
8
8
0
0
8
0
24
0
0
0
16
8
% T
% Val:
8
0
0
0
8
0
0
8
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _